Utilization of Periovance Oral Rinse for Post-Surgical Pain Management

INTRODUCTION

According to the Journal of Dentistry, up to 50% of adults have dental fear.¹  In addition, 1 in 3 Americans avoid the dentist completely due to this fear.² But what do these patients fear the most? The pain associated with dental procedures, especially after dental surgery.  

Managing acute dental pain after a surgical procedure doesn’t have to be challenging for the patient or the clinician. Since it is normal to experience some pain after dental surgeries, the goal of any dentist is to minimize the duration of the post-surgical pain.

CLINICAL EVALUATOR

All post-surgical results were obtained via a controlled study involving patients selected by Dr. Srinivas Myneni, DDS, PhD. Dr. Myneni is a Tenured Associate Professor in the Department of Periodontology & Endodontics at the Stony Brook School of Dental Medicine. He is also an esteemed Director of the Advanced Dental Education Program in Periodontics, the Director of Periodontal Research and a member of OraBio’s Scientific Advisory Board. 

CHALLENGE: Managing Pain Without Pharmaceuticals 

Post-operative pain management is pivotal in the patients' experience of surgical treatments. In addition, due to the complexities of care that can accompany post-surgical dental pain, it is common for surgeons to prescribe pharmaceuticals. Common non-opioid analgesics include acetaminophen (Tylenol), typically dosed at 500-1000 mg every 6 hours as needed for pain, and NSAIDs such as ibuprofen, typically dosed at 400-600 mg every 6 hours. In addition, if necessary for severe pain, opioid analgesics such as hydrocodone

(Vicodin) or oxycodone (Percocet) may be prescribed. 

Recently, several studies and reviews in dental literature have highlighted patient preferences for drug-free pain management options. A survey of post-operative dental patients in the Journal of Oral and Maxillofacial Surgery highlights the desire that patients have for non-pharmacological options.³ Additionally, combining non-pharmacological methods with minimal use of pharmaceuticals, when necessary, is often recommended to meet patient preferences and effectively manage pain. 

SOLUTION: Periovance Oral Rinse for Non-Pharmacological Pain Management 

Periovance Oral Rinse provides fast and effective post-treatment pain relief for dental patients following various surgical procedures, including but not limited to extractions, osseous surgery, periodontal grafting, and periodontal flap surgery. This oral rinse is an easy-to-administer, full-mouth mucosal anesthetic that is needle-free, alcohol-free and delivered with a single 60-second swish. Its unique blend of benzocaine, maltodextrin, xylitol and aloe-vera bind to pain receptors for a complete combination of pain relief and comfort.

STUDY DESIGN 

In this study, patients were assigned the following pain management instructions: 

Use of Periovance Oral Rinse First: Patients were instructed to use Periovance Oral Rinse before taking any non-opioid analgesics (Tylenol/Acetaminophen) or opioid (Percocet) analgesics, to evaluate the rinse's effectiveness as an initial pain management option.

This study design aimed to evaluate the effectiveness of Periovance Oral Rinse as a stand-alone pain management alternative to non-opioid analgesics and opioids. 

In total, 21 independent patient results are discussed below.

RESULTS AND PROOF POINTS

Patients were not solicited by OraBio, Inc. for the purpose of this clinical study. Each patient provided verbal consent to use Periovance Oral Rinse for post-surgical pain management. Patients were aged between 18 and 99, with no bias toward sex or ethnicity.  

The clinical results and in-depth patient interviews clearly support the claim that Periovance Oral Rinse is effective at post-surgical pain management. 

• Pain Reduction: The average initial pain score among participants after surgical anesthesia wore off was 8.0. With the Periovance Oral Rinse use, the pain score was reduced to 2.5. This was among the 76% of participants that did not require any other pain management.
  

• Rescue Pain Management: 76% of participants did not require any additional pain management. Of those participants with initial pain of 9-10, only 50% required rescue pain management. 
  

• Consumer Acceptance: 100% of participants indicated they would want to use Periovance Oral Rinse again to manage at-home pain.

  
  

SUMMARY

Periovance Oral Rinse:

• Provides an effective solution for non-pharmaceutical pain management with 100% of participants wanting to use Periovance Oral Rinse in the future

  
  

• Effectively manages post-surgical pain 

  
  

• 76% of patients did not need pharmaceutical intervention
  

• Helps to improve overall patient care and pain management

STUDY TESTIMONIALS

REFERENCES

1. "Estimated Prevalence of Dental Fear in Adults: A Systematic Review and Meta-Analysis." Journal of Dentistry, vol. 108, May 2021, https://doi.org/10.1016/j.jdent.2021.103632.
   

2. "DentaVox: Over 60% of People Worldwide Suffer from Dental Fear, 4% Have Never Visited a Dentist." BioSpace, 13 Sept. 2018, https://www.biospace.com/article/-dentavox-over-60-percent-of-people-worldwide-suffer-from-dental-fear-4-percent-have-never-visited-a-dentist/. Accessed 26 July 2024.
   

3. “Patient Preferences for Pain Management.” Schiff, T. L., & Degen, L. C. (2015). Journal of Oral and Maxillofacial Surgery, 73(6), 1060-1066